The relationship between pre-mir-146a G/C polymorphism and risk of gastric cancer in patients with gastric cancer in Ardabil province, Iran
نویسندگان
چکیده
منابع مشابه
The Relationship between IL-1β-511 Polymorphism and Gastric Cancer in Ardabil Province, Iran
Background & objectives: Gastric cancer has a very wide geographic distribution. Identification of the genetic factors involved in the cancer predisposition is very important. IL-1β as a pro inflammatory cytokine is involved in gastric acid secretion in the H. pylori infected individuals. This study was aimed to evaluate the role of IL-1β-511 polymorphism on the susceptibility to gastric canc...
متن کاملThe Association of pre-mir-196a2 T/C Polymorphism and Risk of Gastric Cancer in Ardabil, Iran
Micro-RNAs are a large group of non-coding RNAs of 18-25 nucleotides in length. Polymorphisms in the human pre-mir-RNAs could change the efficiency of target cell and can also play a role in cell cycle regulation and cancer. The aim of this study is to investigate the association of rs11614913 T/C polymorphism with gastric cancer risk in Ardabil Province. In a case-control study, this polymorph...
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چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولthe relationship between pre-mir-196a2 t/c polymorphism and risk of gastric cancer in ardabil, iran
micro-rnas are a large group of non-coding rnas with 18-25 nucleotides. polymorphisms in the human pre-mir-rna could change the efficiency of target cell and can also play a role in cell cycle regulation and cancer. the aim of this study was to investigate the association of rs11614913 t/c polymorphism with gastric cancer risk in ardabil province. in a case-control study, this polymorphism was ...
متن کاملmiR-146a in gastric cancer Clinical significance of miR-146a in gastric cancer cases
Purpose: The profiles of microRNAs change significantly in gastric cancer. MiR-146a is reported to be a tumor suppressor in pancreatic cancer, breast cancer and prostate cancer. We investigated the clinical significance of miR-146a in gastric cancer, in particular focusing on hypothetical miR-146a target genes, such as epidermal growth factor receptor (EGFR) and interleukin-1 receptor-associate...
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ژورنال
عنوان ژورنال: International Journal of Advances in Medicine
سال: 2015
ISSN: 2349-3925
DOI: 10.18203/2349-3933.ijam20150548